{"id":4929,"date":"2024-10-07T15:00:30","date_gmt":"2024-10-07T15:00:30","guid":{"rendered":"https:\/\/tradetrovex.com\/index.php\/2024\/10\/07\/nobel-prize-for-medicine-goes-to-american-scientists-who-worked-on-microrna\/"},"modified":"2024-10-07T15:00:30","modified_gmt":"2024-10-07T15:00:30","slug":"nobel-prize-for-medicine-goes-to-american-scientists-who-worked-on-microrna","status":"publish","type":"post","link":"https:\/\/tradetrovex.com\/index.php\/2024\/10\/07\/nobel-prize-for-medicine-goes-to-american-scientists-who-worked-on-microrna\/","title":{"rendered":"Nobel Prize for medicine goes to American scientists who worked on microRNA"},"content":{"rendered":"<p>This year\u2019s Nobel Prize for physiology and medicine has been awarded to two American scientists who discovered how \u201cmicroRNA\u201d controls the decoding of genetic information in living organisms.<\/p>\n<p>Studying the tiny nematode worm C \u201celegans\u201d, Victor Ambros and Gary Ruvkun independently discovered that small sequences of RNA were essential in determining whether certain genes are turned into proteins that carry out life\u2019s functions.<\/p>\n<div class=\"sdc-site-outbrain sdc-site-outbrain--AR_6\">    <\/div>\n<p>\u201cTheir groundbreaking discovery revealed a completely new principle of gene regulation that turned out to be essential for multicellular organisms, including humans,\u201d said Olle Kampe, chair of the <strong>Nobel Prize<\/strong> Committee.<\/p>\n<p>Until their discovery, molecular biologists thought they understood how life controlled the expression of genes: large proteins called transcription factors determined which genes get translated from DNA into its sister molecule RNA before being turned into proteins \u2013 to make new skin, muscle, hormones, or anything else.<\/p>\n<p>The discovery of microRNA was initially thought to be \u201can oddity peculiar to a small worm\u201d, according to Mr Kampe.<\/p>\n<div class=\"ad ad--teads\">        <\/div>\n<p>But Mr Ambros and Mr Ruvkun showed microRNA is found in nearly all complex life forms and plays a fundamental role in regulating how organisms function.<\/p>\n<p>Also, when they misfunction. Errors in microRNA were since found to cause chronic lymphocytic leukaemia, a form of blood cancer.<\/p>\n<p>Since the discovery, new research is exploring the involvement of microRNA in all aspects of biology and many other disease types including other cancers, obesity and heart disease.<\/p>\n<p>The discovery doesn\u2019t have the same immediate application <strong>as last year\u2019s Nobel Prize in medicine<\/strong>, which also went to an RNA discovery \u2013 using the molecule to make vaccines against cancer and diseases like COVID-19 \u2013 but it is so fundamental it is likely to lead to new insights for medicine.<\/p>\n<\/p>\n<div>This post appeared first on sky.com<\/div>\n","protected":false},"excerpt":{"rendered":"<p>This year\u2019s Nobel Prize for physiology and medicine has been awarded to two American scientists&hellip;<\/p>\n","protected":false},"author":0,"featured_media":4930,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[],"class_list":["post-4929","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tech-news"],"_links":{"self":[{"href":"https:\/\/tradetrovex.com\/index.php\/wp-json\/wp\/v2\/posts\/4929","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/tradetrovex.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/tradetrovex.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/tradetrovex.com\/index.php\/wp-json\/wp\/v2\/comments?post=4929"}],"version-history":[{"count":0,"href":"https:\/\/tradetrovex.com\/index.php\/wp-json\/wp\/v2\/posts\/4929\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/tradetrovex.com\/index.php\/wp-json\/wp\/v2\/media\/4930"}],"wp:attachment":[{"href":"https:\/\/tradetrovex.com\/index.php\/wp-json\/wp\/v2\/media?parent=4929"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/tradetrovex.com\/index.php\/wp-json\/wp\/v2\/categories?post=4929"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/tradetrovex.com\/index.php\/wp-json\/wp\/v2\/tags?post=4929"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}